Iran fired on Israel following Israeli strikes in the Lebanese capital Beirut.
President Donald Trump announced "major combat operations" against Iran on Feb. 28, with massive joint U.S.-Israeli strikes targeting military, government and infrastructure sites.
Following the announcement of a two-week ceasefire, initial U.S.-Iran talks in Pakistan in April failed to reach a peace deal.
Trump later announced the open-ended extension of the ceasefire and the continuation of a U.S. blockade until negotiations are concluded "one way or the other."
President Donald Trump and Israeli Prime Minister Benjamin Netanyahu spoke by phone in two separate calls, once on Sunday and once on Monday, after Israel and Iran exchanged strikes over the weekend, a White House official and an Israeli source familiar with the matter confirmed to ABC News.
Israeli Prime Minister Benjamin Netanyahu said in a video statement Monday that "in the past 24 hours, Iran and Hezbollah have tried to impose a new equation on us. And this equation is intolerable and unacceptable."
"Iran and Hezbollah are weaker than ever, and we are stronger than ever -- but our struggle with them is not over yet," Netanyahu said.
He added that the violent flareup from the last day "is contained," but only because strikes on Israel from Iran stopped after Israel struck Iran.
"Israel has a full right to self-defense, and we exercise it to the extent necessary. I say this to you, as I say it with appreciation and respect in my good conversations with my friend President Trump," Netanyahu said.
-ABC News’ Jordana Miller
All flights in Iran have been canceled until further notice in the wake of the closure of western Iranian airspace, the nation's Airports and Air Navigation Company announced Monday, according to Iranian state TV.
The only open airport is Mashhad International Airport, which the AANC said will remain open to facilitate people returning from the Hajj pilgrimage.
-ABC News' Somayeh Malekian
Fifteen Iranians were injured in recent Israeli attacks on the country, the head of Iran's emergency medical services said on Monday, according to the semi-official Tasnim News Agency.
Fourteen of the injuries were reported in Mahshahr and one was in Tehran, he said, adding that no fatalities have been reported so far.
-ABC News' Somayeh Malekian
