B-2 bombers dropped a number of Massive Ordnance Penetrator bombs -- known as "bunker busters" -- during the U.S. mission over Iran, a U.S. official confirmed.
A number of Tomahawk cruise missiles were also fired at targets inside Iran from a U.S. Navy submarine, the official confirmed.
Following the strikes, Trump addressed the nation, calling it a "spectacular military success."
The Israel Defense Forces issued a warning to residents in District 3 of Tehran to "immediately leave" ahead of planned strikes there.
"In the coming hours, the Israeli army will take action in this area to attack the Iranian regime's military infrastructure, just as it has done in recent days around Tehran," a post to the IDF's Farsi-language X account read.
-ABC News' Jordana Miller, Dada Jovanovic and Ellie Kaufman
Jun 16, 2025, 9:23 AM EDT
Israel not seeking regime change in Iran, IDF says
Israel is "not planning to change the regime in Iran," Israel Defense Forces spokesperson Brig. Gen. Effie Defrin told ABC News' Ian Pannell in Tel Aviv on Monday.
Smoke billows from the Shahran oil depot, northwest of Tehran, on June 16, 2025.
Atta Kenare/AFP via Getty Images
"Our military targets, our military goals are to remove this threat, to remove the threat of a nuclear bomb over Israel and the ballistic missiles, and of course the proliferation of terror all over the region," Defrin said.
"It's up to the Iranian people to change the regime, not to us," Defrin said. "We are removing this threat. This is why we paved the way to Iran."
Asked about the growing toll on Israeli civilians as Iran retaliates, Defrin said, "Can you imagine what would have happened if this happens when Iran has nuclear capabilities?" He then suggested that Israel had "only a matter of days" in which to prevent such a development.
Attacks in Iran, Defrin continued, will go on for "as far as we're concerned."
-ABC News' Ian Pannell, Morgan Winsor, Dana Savir, Alessandro Pavone and Gabriella Abdul-Hakim
Jun 16, 2025, 9:04 AM EDT
Israeli control of Tehran airspace changes 'entire' campaign, Netanyahu says
Israel's control of the airspace over Tehran represents a "change in the entire" military "campaign," Israeli Prime Minister Benjamin Netanyahu said in comments on Monday.
Smoke billows for the second day from the Shahran oil depot, northwest of Tehran, on June 16, 2025.
AFP via Getty Images
"When we control the skies over Tehran, we are striking these goals, the regime's targets, in contrast to the criminal regime of Iran that targets our citizens and comes to kill children and women," Netanyahu said.
"We are telling the citizens of Tehran: 'Get out' -- and we are acting," Netanyahu said.
At least 224 people have been killed in Iran since Israel launched its first strikes there on Friday, according to Iranian authorities. At least 24 people have been killed by Iranian retaliatory strikes in Israel, according to Netanyahu's office.
Iran and Israel have both accused the other of striking civilian targets.
-ABC News' Jordana Miller and Ellie Kaufman
Jun 16, 2025, 7:00 AM EDT
IDF says it killed 4 senior Iranian intelligence officials
The Israel Defense Forces said in a Monday statement that it killed four senior Iranian intelligence officials in an airstrike in Tehran.
Smoke rises following what Iran says was an Israeli attack on Sharan Oil depot in Tehran, Iran, on June 16, 2025.
Majid Asgaripour/via Reuters
The IDF said the four officials were killed after an Israeli Air Force strike targeted a "structure in Tehran where several senior officials from Iranian intelligence" were located.
"In the strike, the Head of the Islamic Revolutionary Guard Corps (IRGC) Intelligence Organization and his deputy, as well as the Head of the Quds Force Intelligence Department and his deputy, were all eliminated," the IDF said.