Israel-Iran updates: Iran launches more missiles at Israel, sirens sound in Tel Aviv and Jerusalem

Israeli Air Forces are "completing a wave of strikes against military and strategic assets, nuclear program sites and high-ranking figures," in Iran, the Israel Defense Forces said in a statement Saturday evening local time.

"At this hour, Israeli Air Force pilots continue to conduct widespread strikes across various regions in Iran — an ongoing operation lasting nearly 40 hours and targeting over 150 objectives," IDF spokesman Brig. Gen. Effie Defrin said.

Protective measures will remain in effect in Israel after the IDF conducted a situational assessment, Defrin said. Schools will be closed Sunday, he added.

Israel struck two of Iran’s nuclear facilities in attacks already -- the Natanz enrichment plant and the Isfahan conversion facility, Defrin said.

“The damage to Iran’s nuclear program, missile systems, and terror leadership constitutes a major blow to the existential threat Iran attempts to impose on Israel,” Defrin said.

-ABC News' Jordana Miller

Four critical buildings at the Isfahan nuclear site in Iran "were damaged" in Israel’s Friday attack, the International Atomic Energy Agency said in a post on X Saturday.

The buildings damaged include the Uranium Conversion Facility and the Fuel Plate Fabrication Plant, according to the IAEA.

"As in Natanz, no increase in off-site radiation expected," the IAEA said, referring to another nuclear facility struck.

Russian President Vladimir Putin spoke with Israeli Prime Minister Benjamin Netanyahu and Iranian President Masoud Pezeshkian by phone on Friday, Putin told President Donald Trump during their phone call Saturday, according to Russian Presidential Aide Yuri Ushakov.

"The importance of preventing the escalation of the conflict and the readiness of the Russian side to carry out possible mediation efforts were emphasized," Ushakov told Russian journalists Saturday.

The two leaders also discussed the ongoing war in Ukraine during the call, Ushakov said. Putin told Trump he was willing to continue negotiations with Ukraine after June 22, Ushakov said.

The phone call between Putin and Trump was the third phone call between the two leaders this month, and fifth since the beginning of the year, according to Ushakov.

-ABC News' Tanya Stukalova

Israeli Prime Minister Benjamin Netanyahu vowed to "win" against Iran, saying "there is more to be done," in a recorded video statement on Saturday.

"We paved the way to Tehran and our pilots over the skies of Tehran will deal blows to the Ayatollah regime that they cannot even imagine. I can tell you this, we have indications that senior leaders in Iran are already packing their bags. They sense what's coming," Netanyahu said in a statement.

-ABC News' Jordana Miller