Israel-Gaza-Lebanon updates: IDF orders evacuations in Beirut as huge blast hits city

In his first on-camera remarks since Iran's missile attack, President Joe Biden reiterated the United States' full support of Israel.

"Make no mistake, the United States is fully, fully, fully supportive of Israel," he said.

He said that at his direction, the U.S. military "actively supported the defense of Israel" and while they are still assessing the impact, the attack "appears to have been defeated and ineffective."

Biden said there was "intensive planning" between the U.S. and Israel to "anticipate and defend against the brazen attack we expected."

Asked how he would like Israel to respond, Biden said it was an "active discussion."

"We're gonna get all the data straight," he said. "We’ve been in constant contact with the Israeli government and our counterparts, and that remains to be seen."

-ABC News' Cheyenne Haslett

Talks between the United States and Israel on what a response to Iran's attack should look like are "already underway," State Department spokesperson Matthew Miller told reporters Tuesday.

Those conversations were happening across the State Department, the White House and the Pentagon, he said.

Miller declined to say whether Israel had presented possible targets to the U.S. or if Iran's nuclear facilities might be a legitimate target.

"This is not to say that I'm ruling anything out and that I'm ruling anything in,” he said.

On whether Iran's attack on Israel was over, Miller repeated the U.S. assessment that the current wave has ended, but that he could not definitively say whether there would be additional waves.

"Certainly, it would be incredibly reckless and would continue to be escalatory for Iran to launch further attacks on Israel and we’ll be monitoring in the hours ahead," he said.

-ABC News' Shannon K. Kingston and Emily Chang

Iranian President Masoud Pezeshkian said in a post on X that the attack on Israel was "based on legitimate rights and with the aim of peace and security for Iran and the region."

Pezeshkian also addressed Israeli Prime Minister Benjamin Netanyahu directly in his post: "Let Netanyahu know that Iran is not belligerent, but it stands firmly against any threat."

"This is only a tiny part of our power. Do not step into a conflict with Iran," Pezeshkian added.

-ABC News' Somayeh Malekian

Secretary of State Antony Blinken said Israel appears to have "effectively defeated" Iran's attack.

"A few hours ago, Iran -- for the second time in the space of five months -- launched a direct attack on Israel, including some 200 ballistic missiles. This is totally unacceptable and the entire world should condemn it," he said during a previously scheduled meeting with India's external affairs minister.

National security adviser Jake Sullivan also told reporters during a White House briefing that Iran's attack "appears to have been defeated and ineffective" based on the United States' early assessment.

Sullivan said the U.S. military worked closely with the IDF to defend Israel and was proud to do so, including in shooting down incoming missiles from U.S. naval destroyers positioned in the area, and that President Joe Biden will be involved in constant conversations with the Israelis about what should come next. He declined to provide any details about what level of response Biden will encourage.

-ABC News' Shannon K. Kingston and Cheyenne Haslett